| Date | Location | Result | |
| Nov 13, 2010 | Waynesburg, Pa. | Wash and Jeff 31, Waynesburg 30 | Box score |
| Nov 04, 2010 | Waynesburg, Pa. | Thomas More 14, Waynesburg 10 | Box score |
| Oct 30, 2010 | Latrobe, PA | Waynesburg 34, Saint Vincent 28 | Box score |
| Oct 23, 2010 | Waynesburg, Pa. | Waynesburg 41, Frostburg State 7 | Box score |
| Oct 16, 2010 | Waynesburg, Pa. | Waynesburg 24, Westminster 23 | Box score |
| Oct 09, 2010 | Beaver Falls, PA | Waynesburg 55, Geneva College 42 | Box score |
| Oct 02, 2010 | Bethany, W.Va. | Bethany 24, Waynesburg 17 | Box score |
| Sep 25, 2010 | Waynesburg, Pa. | Waynesburg 42, Grove City 16 | Box score |
| Sep 18, 2010 | Greenville, Pa. | Waynesburg 34, Thiel 6 | Box score |
| Sep 11, 2010 | Edwardsville, PA | Wilkes 38, Waynesburg 35 | Box score |